Revised by a collaborative, international, interdisciplinary team of editors and authors, this edition includes the latest applications of genomics and proteomics and is filled with current findings regarding infectious agents, leading-edge diagnostic methods, laboratory practices, and safety guidelines. This seminal reference of microbiology continues to set the standard for state-of-the-science laboratory practice as the most authoritative reference in the field of microbiology.
“What do you do when your MALDI-TOF reports Sneathia sanguinegens and the doctors is asking what it is, or when you are asked whether a Borrelia recurrentis infection can be treated with ceftriaxone, or whether Coxsackieviruses cause hepatitis? You turn to “THE source” for clinical microbiology information - The Manual of Clinical Microbiology. Whether on your tablet or on the bench; it has what you need.”
—Fred C. Tenover, Vice President, Scientific Affairs, Cepheid
“The Manual of Clinical Microbiology is the key resource for understanding what, why, and how in clinical microbiology. It is truly a must-have document for guiding current practice.”
—Carol A. Rauch, Associate Professor of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center
Two-Volume Hardcover Set, 2,892 pages, full-color illustrations, index.
The Manual of Clinical Microbiology (MCM) is the most authoritative reference text in the field of clinical microbiology. This edition of the Manual benefited from the talents of a team of 22 editors and almost 250 authors who were supported by a very capable production team at ASM Press. This, the 11th edition, is presented after the usual 4-year publication cycle following the 10th edition. All of the editorial team are proud members of the American Society for Microbiology and strong supporters of its book publishing arm, ASM Press. We have followed in the footsteps of previous authors and editors of the Manual and remain steadfastly committed to the utmost quality and timeliness that the MCM readership has come to expect. For the first time, we have had co-editors in chief of MCM. The length and scope of the Manual now require this division of labor to ensure thoroughness and timeliness of the editing process. We hope that readers of the Manual will recognize the commitment to excellence by everyone associated with its production.
We represent only the fifth and sixth editors in chief in the 45-year history of the Manual. We are grateful for the example set by our predecessors and by the sage advice offered by recent editors in chief Patrick Murray and James Versalovic. We offer our deep appreciation to Ken April, the production editor at the outset of this edition, and to Ellie Tupper, who succeeded him and completed the editorial production process.
This is only the second edition of the Manual to have a full-scale, searchable, Web-based HTML electronic edition. We hope that users of the Manual will find this electronic alternative to the print version of MCM to be convenient and user friendly. It is likely that future editions of MCM will rely more heavily on the electronic format for delivery of the vast content of the Manual.
This is a very dynamic era in clinical microbiology, with new technical tools (MALDI-TOF, ribosomal and total gene sequencing, and other molecular methods) that are profoundly influencing our approaches to organism detection and identification. The Manual continues to include classic microbiological techniques such as microscopy and culture as a foundation in addition to the newer methods cited above. Some organisms have become prominent causes of disease recently, e.g., Ebola, enterovirus D-68, and Gram-negative bacteria that produce carbapenemases. Every effort was made to include up-to-date information in the Manual on these recently emergent organisms. In addition, the studies of the human microbiome have informed our understanding of normal microbial communities and have posed the possibility of polymicrobial rather than single-agent infections.
In conclusion, we are profoundly grateful for the privilege of guiding the Manual through the publication of this 11th edition. We hope that the efforts of the editors and authors will prove useful to the clinical microbiology community until the next edition is available in about 4 more years.
JAMES H. JORGENSEN MICHAEL A. PFALLER